If you've already got absorption and OSRS GP overloads, then The only boss who could kill you is corrupt Lizardman. You should disable him so you can't allow him to take you down. There are other bosses who can be tricky to kill but should be in active status as they offer excellent bonus points. However if you are maxed in points and wish to make it easier in the dreams, disable them.
If you are feeling that one of your bosses is causing problems which is why you're not willing be wasting your time fighting him, use Ultimate Force powerup. In other instances, you should avoid using it ,